CAREER
Drug Discovery Scientist
Senior Scientist or Director, Drug Discovery

Location: San Francisco, Bay Area or Shanghai, China

Who we are

  • AceLink is a rapidly growing biopharmaceutical company led by a group of highly motivated and highly experienced drug development professionals.  We leverage strong venture capital support, a product pipeline comprising internal discovery and externally licensed programs, and a network of industry leaders to develop life-transforming therapies for serious kidney diseases.  Our lead program, AL-01, is expected to enter clinical stage in 2021.

Roles

  • Work in a fast-paced environment to design, manage and troubleshoot biology assays as well as pharmacology studies.
  • Collaborate closely with supervisor and chemists, biologists, and clinical development colleagues to identify and advance developments candidates.
  • Work very closely with CROs and academic collaborators, to support identification and characterization of novel therapeutics.
  • Prepare weekly presentations to convey recent findings and influence key decisions.
  • Understand the programs and company goals and deliver results to meet these needs.

Requirements

  • Advanced degree (MS or PhD) with broad experience in drug development including assay development, ADME-PK, and secondary pharmacology.  Kidney and immunology experience a significant plus.
  • 5+ years of drug discovery experience in an industry setting, including an understanding of drug development principles.
  • Proficiency in organizing, analyzing, and presenting data using Microsoft platforms, GraphPad Prism, etc.
  • Ability to articulate scientific data and methods to team members.
  • Fluency in Chinese a plus. 

 Why Acelink?

  • Using cutting edge chemistry, genetics, and biology to develop life-transforming therapies.
  • Fast paced drug discovery environment with the opportunity to participate and gain experience in all areas of the drug development process.
  • Interact and learn from academic and industry leaders and utilize cutting edge technologies from some of the industry’s most innovative CROs.
  • Flexible work environment that emphasizes on achieving company goals and providing career development opportunities.  
Medicinal Chemistry Scientist
Senior Scientist or Director, Chemistry

Location: Shanghai, China

Who we are

  • AceLink is a rapidly growing biopharmaceutical company led by a group of highly motivated and highly experienced drug development professionals.  We leverage strong venture capital support, a product pipeline comprising internal discovery and externally licensed programs, and a network of industry leaders to develop life-transforming therapies for serious kidney diseases.  Our lead program, AL-01, is expected to enter clinical stage in 2021.

Summary

  • The candidate will be stationed in Shanghai, China to manage chemistry projects at local CRO companies, participate in and contribute to medicinal chemistry, and drug discovery programs, and provide administrative oversight to the operation of AceLink-Shanghai entity. The candidate should be very knowledgeable in modern synthetic organic chemistry, medicinal chemistry, and drug discovery and able to work independently as well as in an integrated team environment.

Roles

  • The candidate will be responsible to provide day-to-day oversight to all out-sourced chemistry projects at CRO companies. Responsibilities include developing coherent synthetic strategy, trouble-shooting synthetic issues and providing solutions, coordinating and prioritizing synthetic activities around the medicinal chemistry programs to meet the project goals and timelines, and maintaining effective partnership with CRO companies. The candidate will participate in and contribute to medicinal chemistry programs as well as contribute to other chemistry related activities.  Responsibilities include assisting compound design and development of structure-activity-relationship, participating in the regular project meetings with the teams in US, preparing/presenting update/summary to the project teams, and involving in the development of patent applications. As a senior staff at AceLink-Shanghai entity, the candidate will also assist managing the operation of this office.

Requirements

  • PhD degree in synthetic organic chemistry or medicinal chemistry and a minimum 10 years of experience in medicinal chemistry and drug discovery in pharmaceutical industry. Expertise in modern synthetic methodologies, transformations, and mechanisms.  Experienced and with good track records in compound design, lead optimization, and advancing compounds to pre-clinical development for drug discovery programs. Excellent written and verbal communication skills, self-motivated, strong inter-personal skills and able to effectively interact externally with CRO companies and internally with multidisciplinary teams.

Why Acelink?

  • Using cutting edge chemistry, genetics, and biology to develop life-transforming therapies.
  • Fast paced drug discovery environment with the opportunity to participate and gain experience in all areas of the drug development process.
  • Interact and learn from academic and industry leaders and utilize cutting edge technologies from some of the industry’s most innovative CROs.
  • Flexible work environment that emphasizes achieving company goals and providing career development opportunities.

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